Seminars

Abstract

The immune system consists of two parts: innate immunity and adaptive immunity. T cells and B cells in the adaptive immune system are two major players to mount an antigen-specific defense and offer long-term protection. However, due to the immune tolerance and immunodominance mechanisms, some T cells and B cells can recognize the antigens but couldn’t develop effective immune responses. My research focus is using synthetic materials to engineer the innate immune system and “unlock” the non-responsive adaptive immune repertoire for new cancer immunotherapies and infectious vaccines. In this seminar, two examples illustrating my research work will be described.