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High-speed image sensors & systems for recording neuronal voltage dynamics

Tuesday, January 21, 2025
2:00 pm - 3:00 pm

Location: BME 3.204

Speaker: Jack Zhang, Ph.D
Research Scientist, Brain and Cognitive Sciences
Massachusetts Institute of Technology

ABSTRACT:

Neuronal voltage activity is the basis of communication and computation in neural circuits. However, directly capturing these voltage dynamics in vivo remains a major challenge. I will discuss my work on developing high-speed image sensors and systems for direct optical readout of neuronal voltage signals. I will conclude by discussing my ongoing and future work using these tools to study how different types of cells in the hippocampus interact during learning and memory consolidation - processes central to cognition and frequently disrupted in neurological disorders such as Alzheimer's disease and epilepsy.

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