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"Unlock" the Adaptive Immune Repertoire by Controlling Innate Immunity with Materials
3:30 pm - 5:00 pm
Location: BME 3.204
Speaker: Qian Yin, PhD
Instructor
Institute for Immunity, Transplantation, and Infection Operations
Stanford University
Abstract
The immune system consists of two parts: innate immunity and adaptive immunity. T cells and B cells in the adaptive immune system are two major players to mount an antigen-specific defense and offer long-term protection. However, due to the immune tolerance and immunodominance mechanisms, some T cells and B cells can recognize the antigens but couldn’t develop effective immune responses. My research focus is using synthetic materials to engineer the innate immune system and “unlock” the non-responsive adaptive immune repertoire for new cancer immunotherapies and infectious vaccines. In this seminar, two examples illustrating my research work will be described.