PrivateMultiphoton Microscopy of Nanoshells
Summary
This project seeks to develop nanoshells as combined luminescence imaging and photothermal therapy agents of tumors. Gold nanoshells (dielectric silica core/gold shell) are a novel
class of hybrid metal nanoparticles whose unique optical properties have
spawned new applications including more sensitive molecular assays and
cancer therapy. We have recently reported that nanoshells (NS) glow brightly when excited by near-infrared light. This bright luminescence enables nanoshells as contrast agents for biological imaging applications.
This project represents a collaboration with researchers from Nanospectra Biosciences and UT Austin.
Collaborators:
Jon Schwartz, PhD, Nanospectra Biosciences
Don Payne, Nanospectra Biosciences
Andrew Dunn, PhD, Biomedical Engineering, University of Texas
Funding:
American Society for Laser Medicine and Surgery. PI: James W. Tunnell
