PrivatePublications
Publications
Puvanakrishnan P, Park J, Diagaradjane P, Schwartz JA, Coleman C, Gill-Sharp KL, Sang KL, Payne JD, Krishnan S, Tunnell JW. Near infrared narrowband imaging of gold/silica nanoshells in tumors. J Biomed Opt 14(2):024044, 2009 [PDF]
Erickson T, Tunnell JW. “Gold Nanoshells in Biomedical Applications.” Nanomaterials for the Life Sciences: Mixed metal nanomaterials, Vol. 3 Ed. Chulla Kumar, Wiley-VCH, pgs. 1-44, 2009
Abstracts/Presentations
Rajaram N, Gopal A, Zhang XJ, Tunnell JW. Spectral diagnosis of cutaneous malignancy: effect of pigment packaging on diffuse reflectance measurements. 29th Annual Meeting for the American Society for Laser Medicine and Surgery, Washington, DC, April 1-5, 2009
Park J, Estrada A, Sharp K, Sang K, Schwartz JA, Smith DK, Diagaradjane P, Coleman C, Payne JD, Krishnan S, Korgel BA, Dunn AK, Tunnell JW. Investigation of gold nanoparticle transport kinetics using two-photon induced photoluminescence imaging. 29th Annual Meeting for the American Society for Laser Medicine and Surgery, Washington, DC, April 1-5, 2009
Zaman R, Rajaram N, Walsh A, Oliver J, Rylander HG, Tunnell JW, Welch AJ, Mahadevan-Jansen A. Variation of fluorescence with temperature. 29th Annual Meeting for the American Society for Laser Medicine and Surgery, Washington, DC, April 1-5, 2009
Park J, Estrada A, Schwartz JA, Payne JD, Dunn AK, Tunnell JW. Two photon microscopy of gold nanoparticles bio-distribution in tumors. SPIE International Symposium on Biomedical Optics, San Jose, CA January 24-29, 2009
Puvanakrishnan P, Diagaradjane P, Schwartz J, Payne D, Krishnan S, Tunnell JW. Narrowband imaging of tumors using gold nanoshells. SPIE International Symposium on Biomedical Optics, San Jose, CA January 24-29, 2009
Rajaram N, Kovacic D, Migden MF, Reichenberg J, Nguyen T, Tunnell JW. In vivo spectral analysis of skin cancer. SPIE International Symposium on Biomedical Optics, San Jose, CA January 24-29, 2009
Zaman RT, Rylander III HG, Rajaramn N, Wang T, Asokan N, Tunnell JW, Welch AJ. Morphological and optical properties changes of sclera due to hyper-osmotic agent. SPIE International Symposium on Biomedical Optics, San Jose, CA January 24-29, 2009
Publications
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Rajaram N, Nguyen TH, Tunnell JW. A Lookup-table based inverse model for measuring optical properties of turbid media. J Biomed Opt 13(5):050501, 2008 [PDF]
Diagaradjane P, Shetty A, Wang J, Elliot A, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford J, Cho S, Tunnell JW, Hazle J, Krishnan S. Modulation of in vivo tumor radiation response via vascular-focused hyperthermia – characterizing gold nanoshells as integrated anti-hypoxic and localized vascular disrupting agent. Nano Lett 8(5); 1492-1500, 2008 [PDF]
Park J, Estrada A, Sharp K, Sang K, Schwartz JA, Smith D, Coleman C, Payne JD, Korgel B, Dunn AK, Tunnell JW. Two-photon-induced photoluminescence imaging of tumors using near-infrared excited gold nanoshells. Opt Express 16(3):1590-1599, 2008 [PDF]
Park J, Estrada A, Schwartz JA, Payne JD, Dunn AK, Tunnell JW. 3D Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence. Proc SPIE 6869, 68690L, 2008
Rajaram N, Aramil T, Lee K, Tunnell JW. A clinical instrument for spectral diagnosis of cutaneous malignancy. Proc SPIE 6848, 68480R, 2008 [PDF]
Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park CH, Deorukhar A, Elliot AM, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Gold nanoshell mediated hyperthermia enhances the efficacy of radiation therapy. Proc SPIE 6865, 68650N, 2008
Abstracts/Presentations
Tunnell JW, Park J, Estrada A, Schwartz JA, Dunn AK, Payne JD. Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence. IEEE LEOS. Acapulco, Mexico, July 21-23, 2008
Park J, Estrada A, Schwartz JA, Payne JD, Dunn AK, Tunnell JW. Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence. Conference on Lasers and Electro-optics (CLEO). San Jose, CA, May 2-9, 2008
Rajaram N, Tunnell JW. A look-up table based inverse model for measuring tissue optical properties. OSA Biomedical Optical Spectroscopy and Diagnostics. St. Petersburg, FL, March 16-19, 2008
Feld MS, Lau C, Scepanovic O, McGee SA, Mircovic J, Yu CC, Fulghum S, Tunnell JW, Backman V, Georgakoudi I, and Bechtel K The Role of Light Scattering Spectroscopy in Spectral Diagnosis of Disease. OSA Biomedical Optical Spectroscopy and Diagnostics. St. Petersburg, FL, March 16-19, 2008
Rajaram N, Tunnell JW. A look-up table based inverse model for measuring tissue optical properties. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 7-8, 2008
Rajaram N, Tunnell JW. Determining the optical properties of turbid media using a LUT-based inverse model. Lasers in Modern Biology and Medicine – AJ Welch Symposium. Austin, TX, January 28-29, 2008
Park J, Estrada A, Schwartz JA, Payne JD, Dunn AK, Tunnell JW. 3D Microscopy of gold nanoshells in tumors using two-photon induced photoluminescence. SPIE International Symposium on Biomedical Optics: Plasmonics in Biology and Medicine V, San Jose, CA January 19-24, 2008
Rajaram N, Aramil T, Lee K, Tunnell JW. A clinical instrument for spectral diagnosis of cutaneous malignancy. SPIE International Symposium on Biomedical Optics: Advanced Clinical and Diagnostic Systems VI, San Jose, CA January 19-24, 2008
Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park CH, Deorukhar A, Elliot AM, Stafford JR, Cho S, Tunnell JW, Hazle J, Krishnan S. Gold nanoshell mediated hyperthermia enhances the efficacy of radiation therapy. SPIE International Symposium on Biomedical Optics: Plasmonics in Biology and Medicine V, San Jose, CA January 19-24, 2008
Publications
Zaman RT, Diagaradjane P, Wang J, Swartz J, Rajaram N, Gill-Sharp K, Cho S, Rylander HG, Payne DJ, Krishnan S, Tunnell JW. In vivo detection of gold nanoshells in tumors using diffuse optical spectroscopy. IEEE J Sel Top Quant Elec 13(6):1715-1720, 2007 [PDF]
Abstracts/Presentations
Tunnell JW. Opportunities for biomedical engineering in world health. UT for REED (Rural Enhancement through Education and Design), The University of Texas at Austin, Austin, TX, September 24, 2007
Tunnell JW. Monitoring metal nanoparticles in vivo. Advances in Oncology Institutional Grand Rounds. MD Anderson Cancer Center, Houston, TX, July 13, 2007
Park J, Rajaram N, Tunnell JW. Combined fluorescence and reflectance hyperspectral imaging for cancer detection. Advances in Optics for Biotechnology, Medicine and Surgery – Engineering Conferences International, Naples, Florida June 10-14, 2007
Rajaram N, Aramil T, Lee K, Tunnell JW. A clinical spectrometer for early detection of cutaneous malignancy. Advances in Optics for Biotechnology, Medicine and Surgery – Engineering Conferences International, Naples, Florida June 10-14, 2007
Zaman R, Diagaradjane P, Krishnan S, Tunnell JW. Measuring gold nanoparticle concentrations in tissue using diffuse optical spectroscopy. CLEO. Baltimore, MD, May 6-11, 2007
Park J, Tunnell JW. Combined fluorescence and reflectance hyperspectral imaging for in vivo cancer detection. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 8-9, 2007
Rajaram N, Dagani GT, Fakhoury JR, Zhang X, Tunnell JW. Effect of inhomogeneous distribution of chromophores on diffuse reflectance measurements in tissue. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 8-9, 2007
Zaman R, Swartz J, Wang J, Diagaradjane P, Krishnan S, Tunnell JW. Measuring gold nanoparticle concentrations in tissue using diffuse optical spectroscopy. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 8-9, 2007
Rasoulian M, Voss J, Revia R, Zaman R, Smith DK, Korgel BA, Tunnell JW. Structured illumination tomography using gold nanoparticle contrast agents. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 8-9, 2007
Aramil TJ, Lee K, Rajaram N, Tunnell JW. A clinical spectrometer for the spectral diagnosis of cutaneous melanoma. Houston Society for Engineering in Medicine and Biology (HSEMB). Houston, TX, February 8-9, 2007
Publications
Yu CC, Lau C, Tunnell JW, Hunter M, Kalashnikov M, Fang-Yen C, Fulghum SF, Badizadegan K, Dasari RR, Feld MS. Assessing Epithelial Cell Nuclear Morphology using Azimuthal Light Scattering Spectroscopy. Opt Lett 31(21):3119-3121, 2006
Wallace MB, Sullivan D, Rustgi AK, Tunnell JW, Feld MS, et al. Advanced Imaging and Technology in Gastrointestinal Neoplasia. Gastroenterology 130(4):1333-1342, 2006
Abstracts/Presentations
Tunnell JW, Krishnan S. Thermoradiotherapy – Development and validation of a new paradigm in cancer therapeutics. Annual Biomedical Engineering Conference – UT Center for Biomedical Engineering. MD Anderson Cancer Center, Houston, TX, December 12, 2006
Tunnell JW. Optical strategies for detection, targeting and treatment of cancer. NSF IGERT Seminar, The University of Texas at Austin, Austin, TX December 1st, 2006
Yu CC, Lau C, Tunnell JW, Hunter M, Kalashnikov M, Fang-Yen C, Fulghum SF, Badizadegan K, Dasari RR, Feld MS. Assessing epithelial cell nuclear morphology with azimuthal light scattering spectroscopy. OSA Biomedical Optical Spectroscopy and Diagnostics. Ft. Lauderdale, FL, March 19-22, 2006
Publications
Pikkula BM, Tunnell JW, Chang DW, Anvari B. Effects of droplet velocity, diameter, and film height on heat removal during cryogen spray cooling. Ann Biomed Eng 32(8):1131-1140, 2004 [view PDF]
Tunnell JW , Desjardins A, Galindo L, Georgakoudi I, McGee SA, Mirkovic J, Muller M, Nazemi J, Nguyen FT, Wax A, Zhang Q, Dasari RR, Feld MS. Instrumentation for multimodal spectroscopic diagnosis of epithelial dysplasia. Technol Cancer Res Treat 2(6):505-514, 2003 [view PDF]
Tunnell JW , Haka AS, McGee SA, Mirkovic J, Feld MS. Diagnostic tissue spectroscopy and its applications to gastrointestinal endoscopy. Tech Gastrointestinal Endo 5:65-73, 2003 [view PDF]
Dai T, Pikkula BM, Tunnell JW, Chang D, Anvari B. Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling: an ex-vivo study. Lasers Surg Med 33(1):16-24, 2003
Tunnell JW , Chang D, Johnston C, Torres JH, Patrick CW, Miller MJ, Thomsen SL, Anvari B. Effects of cryogen spray cooling and high radiant exposures on selective vascular injury during laser irradiation of human skin. Arch Dermatol 139:743-750, 2003 (Editorial Review: Anderson RR. Fire and Ice. Arch Dermatol 139:787-788, 2003) [view PDF pt.A] [view PDF pt.B]
Tunnell JW , Wang L, Anvari B. Optimum pulse duration and radiant exposure for vascular laser therapy of dark port-wine stain skin: a theoretical study. Applied Optics 42(7):1367-1378, 2003 [view PDF]
Pikkula BM, Tunnell JW, Anvari B. Methodology for characterizing heat removal mechanism in human skin during cryogen spray cooling. Ann Biomed Eng 31:493-504, 2003 [view PDF]
Tunnell JW , Torres JH, Anvari B. Methodology for estimation of time-dependent surface heat flux due to cryogen spray cooling. Ann Biomed Eng 30:19-33, 2002 [view PDF]
Pikkula BM, Torres JH, Tunnell JW, Anvari B. Cryogen spray cooling: implications of droplet size and spray density on heat removal. Lasers Surg Med 28:103-112, 2001 [view PDF]
Torres JH, Tunnell JW, Pikkula BM, Anvari B. An analysis of heat removal during cryogen spray cooling and effects of simultaneous airflow application. Lasers Surg Med 28:477-486, 2001 [view PDF]
Tunnell JW , Nelson JS, Torres JH, Anvari B. Epidermal protection with cryogen spray cooling during high fluence pulsed dye laser irradiation: an ex vivo study. Lasers Surg Med 27(4):373-383, 2000 [view PDF]
Abstracts/Presentations
Tunnell JW. Detection of dysplasia and metaplasia in the esophagus using optical spectroscopy. Annual Biomedical Engineering Conference – UT Center for Biomedical Engineering. MD Anderson Cancer Center, Houston, TX, December 12-13, 2005
Tunnell JW . Real-time multi-modal optical spectroscopy for early cancer detection. Engineering Conferences International – Advances in Optics for Biotechnology, Medicine, and Surgery. Copper Mountain, CO, July 24-28, 2005
Tunnell JW . Real-time spectral diagnosis of precancer. 4 th International Cervical Cancer Meeting. MD Anderson Cancer Center, Houston, TX, May 19-22, 2005
Tunnell JW . Real-time detection of dysplasia in patients with Barrett’s esophagus. Lester Wolfe Workshop – Massachusetts Institute of Technology. Cambridge, MA, April 12, 2005
Wallace MB, Tunnell JW, Jost C, Lewin D, Wildi S, Badizadegan K, Galindo L, McGee S, Mirkovic J, Nazemi J, Dasari RR, Feld MS. Real-time optical detection of dysplasia in Barrett’s esophagus using tri-modal (diffuse reflectance, fluorescence, light-scattering) spectroscopy. American Gastroenterological Association – Digestive Disease Week 2005. Chicago, IL May 14-19, 2005
Tunnell JW and Feld MS. Spectroscopic imaging of colon dysplasia. NIH/AGA Symposium on Advanced Imaging and Technology in Gastrointestinal Neoplasia. Bethesda, MD, October 4-5, 2004
Tunnell JW and Feld MS. Spectroscopy, fluorescence imaging, and reflectance imaging. NIH/AGA Symposium on Advanced Imaging and Technology in Gastrointestinal Neoplasia. Bethesda, MD, October 4-5, 2004
Tunnell JW , Desjardins A, McGee SA, Mirkovic J, Nazemi J, Badizadegan K, Dasari RR, Feld MS. Real-time in vivo diagnosis of epithelial precancer using multimodal optical spectroscopy. Great Lakes Photonics Symposium. Cleveland, OH, June 7-11, 2004
Tunnell JW , Desjardins A, McGee SA, Mirkovic J, Nazemi J, Dasari RR, Feld MS. Effects of epithelial nuclear size and density on elastic scattering spectroscopy: an experimental study using two-layer tissue phantoms. OSA Biomedical Optical Spectroscopy and Diagnostics. Miami, FL, April 14-17, 2004
Tunnell JW , Wang LH, Anvari B. Increased radiant exposures for cutaneous laser therapy: a mathematical model based on histology. 2 nd Joint Meeting of the IEEE-EMBS/BMES. Houston, TX, October 23-26, 2002
Pikkula BM, Tunnell JW, Anvari B. Methodology for estimating instantaneous heat removal from human skin in response to cryogen spray cooling. 2 nd Joint Meeting of the IEEE-EMBS/BMES. Houston, TX, October 23-26, 2002
Dai T, Tunnell JW, Pikkula BM, Anvari B. High incident fluence and long pulse laser irradiation in conjunction with cryogen spray cooling: an ex-vivo study. 2 nd Joint Meeting of the IEEE-EMBS/BMES. Houston, TX, October 23-26, 2002
Pope KA, Tunnell JW. Radio frequency energy delivery to the skin: computer model with contact cooling and histology. 22 nd Annual Meeting for American Society for Laser Surgery and Medicine. Atlanta, GA, April 10-14, 2002
Tunnell JW , Wang L, Anvari B. Protecting human skin epidermis with cryogen spray cooling during laser therapy: comparisons between mathematical model and histological results. 22 nd Annual Meeting for American Society for Laser Surgery and Medicine. Atlanta, GA, April 10-14, 2002
Pikkula BM, Tunnell JW, Anvari B. Cryogen spray cooling: effect of droplet velocity on heat removal. 22 nd Annual Meeting for American Society for Laser Surgery and Medicine. Atlanta, GA, April 10-14, 2002
Tunnell JW , Stern RA, Pope KA. Capacitive RF electrode for non-ablative cutaneous thermal therapy. SPIE International Symposium on Biomedical Optics: Cutaneous Applications of Lasers: Dermatology and Plastic Surgery. San Jose, CA, January 19-25, 2002
Tunnell JW , Chang D, Johnston C, Torres JH, Patrick CW, Miller MJ, Anvari B. In-vivo study of epidermal protection by cryogen spray cooling during high fluence laser irradiation. SPIE International Symposium on Biomedical Optics: Cutaneous Applications of Lasers: Dermatology and Plastic Surgery. San Jose, CA, January 19-25, 2002
Tunnell JW , Torres JH, Milner TE, Anvari B. Skin thermal response to cryogen spray cooling using and inverse heat transfer formulation. 21 st Annual Meeting for American Society for Laser Surgery and Medicine. New Orleans, LA, April 18-22, 2001
Tunnell JW , Chang D, Johnston C, Torres JH, Patrick CW, Miller MJ, Anvari B. Epidermal protection during high fluence laser irradiation using cryogen spray cooling: and in vivo study. Nineteenth Annual Houston Conference on Biomedical Engineering Research. Houston, TX, February 8-9, 2001
Tunnell JW , Torres JH, Anvari B. High fluence dermatological laser surgery using cryogen spray cooling. Optical Society of America Annual Meeting. Providence, RI, October 22-26, 2000
Tunnell JW , Nelson JS, Torres JH, Anvari B. Epidermal protection with cryogen spray cooling during high fluence pulsed dye laser irradiation: an ex vivo study. 20th Annual Meeting for American Society for Laser Surgery and Medicine, Reno, NV, April 7-9, 2000
Tunnell JW , Nelson JS, Torres JH, Anvari B. Protecting human epidermis from high fluence pulsed dye laser irradiation with cryogen spray cooling: an ex vivo study. Eighteenth Annual Houston Conference on Biomedical Engineering Research. Houston, TX, February 10-11, 2000