Seminars

R.B. Trull Endowed Lectureship - Modulating the Therapeutic Microenvironment using Nanostructured Biomaterials

Thursday, May 3, 2018
3:00 pm - 4:00 pm

Location: BME 3.204

Speaker: Tejal Desai, PhD
Chair and Professor of the Department of Biomedical Engineering and Therapeutic Sciences
Head of the Therapeutic Microtechnology and Nanotechnology Laboratory
University of California, San Francisco

The field of nanomedicine offers great potential to revolutionize clinical care, including medical devices, regenerative medicine, and molecular imaging approaches. Recent advancements in nanofabrication applied to biocompatible materials lay the groundwork for creating biomaterials with a high level of control at the molecular scale. These subtle interactions with cell and tissue assemblies can modulate properties such as mechanotransduction, adhesion, and immune activation. Nanostructured biomaterials may offer potential advantages over conventional drug delivery strategies by enhancing molecular transport and uptake. In this talk, I will discuss our recent work in developing nanostructured materials for protein and cell-based delivery as well as injectable micro/nanoscale materials for the modulation of fibrosis and immune activation. By gaining a better understanding of how small scale topographies can influence the biological microenvironment, we can design platforms for applications in therapeutic delivery and tissue regeneration.